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Migraine Science
Research breakdowns, treatment guides and myth-busting, written in plain language with the studies linked. No paywalls, ever.
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How migraine works
The Relationship Between Neck Pain and Migraine
How neck pain and migraine are connected, and what that means for treatment.
How migraine works
Understanding Cortical Spreading Depression in Migraine
What cortical spreading depression is and how it drives migraine aura.
How migraine works
Patent Foramen Ovale (PFO) and Migraine: Is there a relationship?
Is a patent foramen ovale linked to migraine? A look at the evidence.
How migraine works
Migraine Phases
A guide to the phases of a migraine attack, from warning signs to recovery.
Prevention
Biofeedback Types for Migraine Treatment
The main types of biofeedback for migraine and how they can reduce attacks.
Research news
Chronic Pain Conditions Associated with Migraine
Fibromyalgia, IBS and other chronic pain conditions that often occur with migraine.
Headache types
Understanding Migraine in the Elderly
Migraine in older adults often looks different, and treatment needs extra care.
Research news
Novel Treatments and Approaches in Migraine Research (as of February 2025)
Novel Treatments and Approaches in Migraine Research (as of February 2025)
How migraine works
Brain Connectivity Changes During Migraine Cycle
Brain scans show connectivity rises and resets across the migraine cycle.
How migraine works
Do Migraine Treatments Reduce Stroke Risk?
In 22,000 patients, propranolol was linked to lower stroke risk in women with migraine.
CGRP
Groundbreaking study!: Anti-CGRP Monoclonal Antibodies Disease-Modifying!?
A three-year study suggests CGRP antibodies may change the course of migraine.
How migraine works
The Case Against Classifying Migraine as Nociplastic Pain
The Case Against Classifying Migraine as Nociplastic Pain
Women's health
Migraine: Men Vs Women
Sex-Based Differences in Migraine
Prevention
Preventive Migraine Medications with a Higher Likelihood of Being Safely Combined
Which migraine preventives are more likely to be safe to combine.
Research news
Global Migraine Trends Analysis
Migraine affects about 1 in 7 people worldwide, and cases rose 58% from 1990 to 2021.
Prevention
How Migraine Medications Are Tested
How migraine medications are tested for safety and effectiveness before approval.
Headache types
Resistant migraine (ResM) Vs Refractory migraine (RefM) Vs Non-resistant/non-refractory migraine (NRNRM)
How resistant and refractory migraine differ, based on the REFINE study.
Aura
Aura Characteristics in Migraine Disease
What migraine aura looks like: 26 visual symptom types, how long they last, and who gets them.
Headache types
Migraine, Cluster, Tension-Type, and Hypnic Headaches: A Complete Timeline Guide
Migraine, Cluster, Tension-Type, and Hypnic Headaches: A Complete Timeline Guide
Headache types
Medication Overuse Headache aka Medication Adaptation Headache aka Rebound Headache: A Comprehensive Guide
Medication overuse headache explained, from causes to treatment, in non-stigmatizing terms.
Lifestyle and triggers
The Migraine Trigger Myth: Why We're Often Wrong About What Causes Our Headaches
Research suggests people are often wrong about what triggers their migraine attacks.
Lifestyle and triggers
Top Migraine Tracking Apps
Table with the top migraine tracking apps for iOS and Android
Devices
My 6 Favorite HeadaTerm 2 Features
A review of HeadaTerm 2, a lower-cost device that uses the same approach as Cefaly.
How migraine works
