
Migraine Science
Research breakdowns, treatment guides, and myth-busting you can actually trust. No paywalls, ever.
MigraineScience
Mon, Jul 13, 26
Rimegepant for Migraine Prevention: Real-World Evidence
New real-world data on rimegepant for migraine prevention: a 75 mg every-other-day gepant that also treats attacks. What the GEMA study found on response rates, dosing, and why earlier use...
Read MoreMon, Jul 13, 26
Placebo Response in Migraine Trials: What a 126-Study Analysis Found
A new Neurology meta-analysis of 126 acute migraine trials found that about 1 in 9 people reach 2-hour pain freedom on placebo alone, and that placebo response has been rising...
Read MoreWe Lined CROWN Up Against the Other Migraine Rollers. Here's Why It Wins.
We put CROWN next to the migraine rollers people reach for most, Migrastil and MigreLief, and compared what is actually in each bottle. Disclosed concentrations, real menthol dosing, no lavender,...
Read MoreMon, Jul 06, 26
Atogepant and Weight: What a One-Year Study Found
A phase 3 open-label extension followed nearly 600 people taking atogepant [Qulipta] for migraine prevention and tracked their weight for a year. Mean weight went down, and about 3 in...
Read MoreMon, Jul 06, 26
Migraine and Blood Sugar: New Low-Glycemic Diet Trial
A large new randomized trial shows that personalized low-glycemic nutrition can lower monthly migraine days. Here is what the blood sugar and migraine link means for prevention, and how to...
Read MoreTue, Jun 30, 26
Is Migraine a Spectrum, Not Two Separate Conditions?
A large study of more than 36,000 adults across 14 countries found that migraine burden rises smoothly with attack frequency, with no sharp jump at the chronic migraine threshold. The...
Read MoreTue, Jun 30, 26
CGRP Migraine Drugs and Blood Pressure: What to Know
A new meta-analysis of 19 randomized trials weighs whether CGRP migraine preventives like erenumab raise blood pressure, and what it means for monitoring.
Read MoreMon, Jun 22, 26
Fremanezumab for Migraine: What Real-World Use Shows
A 2026 real-world meta-analysis found fremanezumab cut monthly migraine days by nearly 6, with about half of people achieving a 50% or greater drop in attacks. Here is what it...
Read MoreMon, Jun 15, 26
Can a Blood Test Measure Your Migraine? What a Large CGRP Study Found
A large Neurology study measured plasma CGRP in 588 people with migraine and found levels were lower than in healthy controls, not higher, and did not track with attacks or...
Read MoreCGRP and Migraine: The Molecule and the New Drugs
CGRP is the molecule behind the newest migraine drugs. What CGRP is, how it triggers an attack, and how anti-CGRP antibodies and gepants prevent or stop attacks, with figures.
Read MoreSat, Jun 13, 26
Sleep and Migraine: How the Two Affect Each Other
Sleep and migraine run on shared brain circuits, so each affects the other. Learn the triggers, the weekend lie-in trap, sleep habits that help, and when to check for apnea.
Read MoreSat, Jun 13, 26
Pediatric Migraine: How It Differs in Kids and Teens
Migraine in kids and teens looks different: shorter, both-sided, stomach-heavy attacks. Learn how to treat them, why lifestyle leads prevention, and the red flags to watch.
Read MoreSat, Jun 13, 26
Menstrual Migraine: Why Your Period Triggers Attacks
Migraines that strike around your period are driven by an estrogen drop. Learn the menstrual window, the two types, timed prevention, and the aura safety rule.
Read MoreSat, Jun 13, 26
Retinal Migraine: Vision Loss in One Eye Explained
Retinal migraine causes brief vision loss in one eye. Learn how to tell it apart from a stroke, how it is diagnosed, which triggers matter, and how it is treated.
Read MoreTue, Jun 09, 26
Migraine and Stroke Risk After Menopause: What a 130,000-Woman Study Found
A new Neurology study of 130,000 postmenopausal women followed for two decades finds a history of migraine is linked to a modest increase in ischemic stroke risk, with no rise...
Read MoreTue, Jun 09, 26
CROWN: The Migraine Roller by Cerebral Torque
Crown is the first migraine roller built on evidence from two traditions. Menthol with the strongest clinical backing, Bing Pian and Chuan Xiong from traditional Chinese medicine, and magnesium. Here's...
Read MoreMigraine Preventive Medications: Which Work Best (2026)
A new 199-trial network meta-analysis ranks migraine preventive medications by both effectiveness and tolerability. Here is what it found about beta-blockers, CGRP-targeted therapies, calcium channel blockers, and anticonvulsants.
Read MoreCandesartan for Migraine Prevention: What New Research Shows
New 2026 research shows candesartan, a low-cost blood pressure pill, can prevent migraines. Here is what the evidence says about how ARBs work, dosing, safety, and who should consider them.
Read MoreFri, May 08, 26
Does the Side of Your Migraine Actually Matter?
If you've been told your migraine attacks are damaging your brain or that the side they're on predicts anxiety or PTSD, the evidence doesn't support it.
Read MoreMigraine, Menopause, and Hormonal Health
Migraine affects women three times more than men, and menopause does not always bring relief. Nearly half of women continue having migraine attacks after menopause. Learn what the research says...
Read MoreWed, Jan 14, 26
New Emergency Department Migraine Treatment Guidelines
The American Headache Society (AHS) has released its 2025 guideline update for the acute treatment of migraine in adults presenting to the emergency department. This update, published in Headache in...
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