MigraineScience

Discover the evolution of ergot alkaloids from ancient remedies to modern migraine treatments. Learn about dihydroergotamine (DHE) formulations including Trudhesa, Atzumi nasal powder, and Brekiya autoinjector - breakthrough FDA-approved therapies...

Learn about migraine comorbidities: how headaches connect to depression, sleep issues, heart disease & more. Guide to comprehensive migraine care for better health outcomes.

COVID-19 worsens migraine patterns in patients with pre-existing migraines, causing increased frequency, severity, and treatment resistance. New research reveals 6 of 7 patients experienced major changes post-infection, with reduced medication...

Comprehensive guidance on managing migraine and headaches during pregnancy and postpartum. Learn about effective treatments, safety considerations, and when to seek medical help. Discover evidence-based strategies for relief, including medication...

A comprehensive guide to medication classes, efficacy, dosing, and considerations for personalized preventive treatment

Table of modifiable migraine risk factors based on recent research

Discover the surprising connection between migraine and cardiovascular health in our latest article. New research reveals how migraine, especially with aura, affects heart health differently than traditional risk factors. Learn...

 Learn how migraine increases stroke risk and discover evidence-based prevention strategies from the latest AHA/ASA guidelines. Practical tips on diet, exercise, medication, and hormonal considerations specifically for migraine patients. Essential...

Key findings from current research on how chronic migraine affects brain structure and function, recent neuroimaging advances, and associated comorbidities.

Discover how treating subclinical hypothyroidism with low-dose levothyroxine may reduce migraine frequency by 28%. Learn about TSH levels, treatment guidelines, and when intervention is recommended.

Fremanezumab (Ajovy) for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder Findings from the UNITE randomized clinical trial involving 353 patients with both migraine and depression Based...

New research reveals increased cerebral blood flow in migraine patients between attacks. This 4D flow MRI study shows significant hemodynamic changes in the middle and posterior cerebral arteries, with blood...

Discover how migraine affects pregnancy outcomes: New meta-analysis reveals increased risks of preeclampsia and preterm birth. Essential reading for patients and clinicians.

Discover how migraine increases cardiovascular disease risk by 12%, with young women facing 60% higher risk. Learn about the significant interaction between migraine and lifestyle factors that could impact heart...

Is Botox (OnabotulinumtoxinA) safe for pregnant migraine sufferers? Review current research, FDA classification, and clinical recommendations for using Botox injections during pregnancy and breastfeeding. Learn about safety data from studies...

Comprehensive expert guide to migraine treatments: evidence-based recommendations for acute medications (NSAIDs, triptans, gepants), preventive therapies, and special considerations for pregnancy, cardiovascular disease, and other medical conditions. Find effective strategies...

Discover evidence-based guidelines for migraine treatment from leading experts. Learn about effective medications for acute attacks and prevention, their evidence quality, and recommendation strength to better manage your migraines.

Discover key predictors of Aimovig (erenumab) response in migraine patients. This REFORM study reveals which patients benefit most from CGRP therapy and why timing matters. Evidence-based insights for better treatment...