Chronic Daily Headache

Chronic Daily Headache

Cerebral Torque

Definition

Chronic daily headache (CDH) is not a formal diagnosis in the International Classification of Headache Disorders, 3rd edition (ICHD-3). Rather, it is an umbrella term used to describe a range of primary and secondary headache disorders characterized by duration and/or frequency depending on the specific headache type. For example, some long CDH subtypes (see below) must persist for 15 or more days per month for at least 3 months while shorter duration CDH subtypes- e.g., cluster or paroxysmal hemicrania- must persist for at least one year without remission or with remissions lasting less than three months.

So while not a distinct diagnosis itself, chronic daily headache encompasses a group of headache disorders marked by extremely frequent headache attacks.

 

Epidemiology

- CDH has an estimated worldwide prevalence of around 4% in adults. It is 2-3 times more common in females.

- The most common headache types underlying CDH are chronic tension-type headache and chronic migraine. CDH results in substantial disability and economic costs.

 

CDH Subtypes

The main CDH subtypes of long duration (≥4 hours per headache) are:

  - Chronic migraine: evolution from episodic migraines, migraine features on ≥ 8 days/month

  - Chronic tension-type headache: pressing, bilateral pain without migraine features

  - Medication overuse/adaptation headache: worsening headaches due to overuse of acute medications

  - Hemicrania continua: unilateral, moderate pain with cranial autonomic symptoms

  - New daily persistent headache: daily headaches without characteristic features

https://www.cerebraltorque.com/blogs/migrainescience/new-daily-persistent-headache-ndph

Other shorter duration headaches (<4 hours per headache) can also be chronic, like:

  - Chronic cluster headache

  - Chronic paroxysmal hemicrania

  - Short-lasting unilateral neuralgiform headache attacks

https://www.cerebraltorque.com/blogs/migrainescience/trigeminal-autonomic-cephalalgias

  - Hypnic headache

https://www.cerebraltorque.com/blogs/migrainescience/hypnic-headache

  - Primary stabbing headache

https://www.cerebraltorque.com/blogs/migrainescience/primary-stabbing-headache-aka-ice-pick-headache-symptoms-pathophysiology-diagnosis-and-treatment

 

Diagnosis

CDH diagnosis depends on meeting criteria for specific headache types after excluding secondary causes.

- Most patients have an unrevealing history and normal neurological exam.

- Further diagnostic testing is based on the presence of "red flags" like:

https://www.cerebraltorque.com/blogs/migrainescience/do-i-need-neuroimaging-for-my-headache

- Differential includes secondary headaches from infections, mass lesions, vascular disorders, etc. See link above for more information.

 

Treatment

Treatment focuses on the specific CDH diagnosis and preventing medication overuse/adaptation headache.

- Chronic migraine: preventives, avoidance of triggers, acute medications, assess for medication overuse/adaptation headache.

Acute: https://www.cerebraltorque.com/blogs/migrainescience/acute-migraine-treatment-cheat-sheet

Prevention: https://www.cerebraltorque.com/blogs/migrainescience/chronic-migraine-preventives

- Chronic tension-type headache: preventives, behavioral and physical therapy 

Acute: https://www.cerebraltorque.com/blogs/migrainescience/acute-treament-of-tension-type-headache-tth

Prevention: https://www.cerebraltorque.com/blogs/migrainescience/tension-type-headache-preventive-treatment

- Medication overuse/adaptation headache: Establish preventives

https://www.cerebraltorque.com/blogs/migrainescience/medication-overuse-headache-moh-treatment-has-changed-mots-medication-overuse-treatment-strategy-trial

- Other CDH subtypes have more specific treatments e.g. indomethacin for hemicrania continua

https://www.cerebraltorque.com/blogs/migrainescience/trigeminal-autonomic-cephalalgias

Back to blog
  • A Breakthrough on the Horizon: PACAP-Targeting Antibodies Offer New Promise for Migraine Prevention

    A Breakthrough on the Horizon: PACAP-Targeting ...

    Cerebral Torque

    Migraine patients may soon have a new treatment option. Recent clinical trials show promising results for Lu AG09222, a monoclonal antibody targeting PACAP, a neuropeptide involved in migraine pathophysiology.

    A Breakthrough on the Horizon: PACAP-Targeting ...

    Cerebral Torque

    Migraine patients may soon have a new treatment option. Recent clinical trials show promising results for Lu AG09222, a monoclonal antibody targeting PACAP, a neuropeptide involved in migraine pathophysiology.

  • New Study Maps Migraine Symptoms Across Attack Phases

    New Study Maps Migraine Symptoms Across Attack ...

    Cerebral Torque

    Symptom Pre-headache* Headache* Post-headache* Interictal* Pooled %** Notes Head pain 50% 100% 28% 5% 100% Only universally reported symptom; defining feature of headache phase Light sensitivity 75% 80% 30% 13%...

    New Study Maps Migraine Symptoms Across Attack ...

    Cerebral Torque

    Symptom Pre-headache* Headache* Post-headache* Interictal* Pooled %** Notes Head pain 50% 100% 28% 5% 100% Only universally reported symptom; defining feature of headache phase Light sensitivity 75% 80% 30% 13%...

  • White Matter Lesions in Migraine Patients: What You Need to Know

    White Matter Lesions in Migraine Patients: What...

    Cerebral Torque

    Discover what white matter lesions mean for migraine patients. This guide explores the latest research on the relationship between migraine and brain changes, offering insights into prevalence, potential causes, and...

    White Matter Lesions in Migraine Patients: What...

    Cerebral Torque

    Discover what white matter lesions mean for migraine patients. This guide explores the latest research on the relationship between migraine and brain changes, offering insights into prevalence, potential causes, and...

  • Gepant Adverse Events Chart

    Gepant Adverse Events Chart

    Cerebral Torque

    A comprehensive analysis of real-world data has uncovered important insights into the safety profiles of gepant medications used for migraine treatment. The study, which examined adverse events reported in the...

    Gepant Adverse Events Chart

    Cerebral Torque

    A comprehensive analysis of real-world data has uncovered important insights into the safety profiles of gepant medications used for migraine treatment. The study, which examined adverse events reported in the...

1 of 4