Frequently Asked Questions*

What is Cerebral Tranquility?

Cerebral Tranquility is a watermelon-flavored gummy (naturally flavored) containing CBN and melatonin. It is specifically designed to help those suffering from migraine by targeting common issues associated with migraine like inflammation, pain signaling, sleep disturbances, and mood instability.

What is CBN and how can it help with migraine?

CBN stands for cannabinol. It is a non-psychoactive cannabinoid that shows promise for reducing inflammation, easing pain, relaxing muscles, stabilizing moods, and improving sleep- all of which could provide support for those with migraine. Emerging research suggests CBN may be uniquely equipped to address migraine due its ability to restore deficiencies in the body's endocannabinoid system and regulate pain and inflammation pathways.

What is melatonin and how can it help with migraine?

Melatonin is a hormone that regulates circadian rhythms and sleep/wake cycles. Studies show melatonin levels are lower in migraine sufferers and sleep issues often trigger attacks. Melatonin possesses antioxidant, anti-inflammatory and pain modulating properties. Supplementing with melatonin may help restore normal melatonin rhythms, improve sleep quality, dampen pain signaling, and ultimately reduce migraine frequency and severity.

Why combine CBN and melatonin?

CBN and melatonin work synergistically together to ease tension, calm nerves, reduce pain signaling, and promote relaxation- all of which can mitigate migraine symptoms and severity. They tackle migraine from multiple angles, providing more complete support.

What is the dosage of Cerebral Tranquility?

Each gummy of Cerebral Tranquility contains 10 mg of CBN and 5 mg of melatonin. The suggested dosage is 1-2 gummies 30 minutes before bedtime. Up to 3 may be used. The dosage is based on studies.

How long until I see results?

Most users report noticeable improvements in sleep quality, relaxation, and migraine pain levels within 1-2 weeks of consistent use. Full effects may take 4-6 weeks (and even up to 3 months) as CBN and melatonin levels build up and restore normal functioning.

Are there any side effects or safety concerns?

CBN and melatonin have excellent safety profiles with minimal side effects comparable to placebo in studies. Some users may experience morning grogginess if taken right before bed or too high of a dose. Start with 1 gummy and adjust timing to optimize results and avoid morning drowsiness. It is best to take 1.5 hours to 30 minutes before bed.

Can I take Cerebral Tranquility long-term?

Yes. Unlike some migraine medications, CBN and melatonin are safe for long-term daily use with no building tolerance or risk of rebound headaches (medication overuse/adaptation headache). In fact, their benefits may increase over time. Most studies show continued efficacy in long-term use of years to decades.

Is Cerebral Tranquility addictive?

No, neither CBN nor melatonin have any addictive properties. They work naturally with your body’s endocannabinoid and circadian systems.

Do I need to worry about failing a drug test after taking Cerebral Tranquility?

No, CBN and melatonin will NOT cause someone to fail any standard workplace drug tests. Both are non-psychoactive compounds isolated from hemp so you will not test positive for THC or other controlled substances.

Our CBN is pure, lab tested, and produced in an FDA-certified facility. There is ZERO chance of contamination.

What is the endocannabinoid system (ECS) and how is it related to migraine?

The ECS regulates many critical bodily processes like pain modulation, inflammation, mood, memory, appetite, and more. Research suggests deficiencies in endocannabinoid signaling contribute to migraine. Restoring balances through plant-derived CBN could alleviate migraine frequency and symptoms.

Why are melatonin levels low in migraine sufferers?

Studies show many people with migraine have significantly decreased melatonin levels. This results from dysregulation of melatonin synthesis in the hypothalamic-pineal axis. Correcting this deficiency through supplementation may provide therapeutic effects.

What dose of melatonin has been found effective for migraine prevention?

Positive outcomes for migraine patients correlate with higher melatonin doses in some analyses. 3-5 mg nightly for 2-3 months is suggested as optimal for migraine support. Cerebral Tranquility contains evidence-based 5 mg melatonin.

How long does it take to see results from CBN?

Plasma CBN levels peak around 1.5 hours after dosing. Most users report noticeable improvements in sleep, relaxation, and migraine pain within 1-2 weeks, but full therapeutic effects likely take 4-6 weeks of sustained use as CBN builds up.

Has CBN demonstrated ability to cross the blood-brain barrier?

Yes, several studies have provided evidence that CBN effectively crosses the blood-brain barrier and enters the central nervous system after oral dosing. This allows CBN to directly act on pain and inflammation pathways involved in migraine.

What is the difference between CBN and CBD? Why choose CBN for migraine?

Unlike CBD, CBN demonstrates greater binding and activity at CB1 receptors - primary endocannabinoid receptors abundant in pain pathways. This suggests CBN more directly impacts signaling involved in migraine pain compared to CBD.

Why can't I use a full spectrum CBD that also has CBN?

It is difficult for most companies to extract CBN so they sell full spectrum CBD as if that's a good thing. Extracting CBN without the other cannabinoids requires state-of-the-art equipment that the other companies just don't have.

The following are 2 studies that show the addition of CBD to either CBN or THC results in reduced sleep quality. Sleep quality is essential to people with migraine as decreased quality of sleep is a common trigger.

Study 1

Study 2

Do the gummies have artifical color or flavorings? Those trigger my migraine attacks?

No. Cerebral Tranquility does not use any artifical colors, perservatives, or flavors. The gummies are 100% vegan, gluten-free, and non-GMO.

These statements have not been evaluated by the Food and Drug Administration.  This product is not intended to diagnose, treat, cure or prevent any disease.*