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Neuromodulation for Migraine: Do the Devices Work?
A new network meta-analysis of 28 randomized trials shows noninvasive neuromodulation devices can cut monthly migraine days without drugs. Here is how they work, which have...
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Menstrual Migraine: Why Your Period Triggers Attacks
Migraines that strike around your period are driven by an estrogen drop. Learn the menstrual window, the two types, timed prevention, and the aura safety rule.
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The Case Against Classifying Migraine as Nociplastic Pain
Why migraine should not be classified as nociplastic pain, and how that label could affect how patients are treated and taken seriously.
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Understanding Cutaneous Allodynia in Migraine
Learn about skin hypersensitivity affecting 63% of migraine patients, validated assessment tools, suicide risks, and how allodynia predicts treatment response. Evidence-based insights from major population studies...
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Migraine with Brainstem Aura
Comprehensive guide to Migraine with Brainstem Aura (MBA) - symptoms, diagnosis, treatment options, and latest research on whether it actually affects the brainstem. Patient-friendly explanations included.
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The Migraine Brain Does NOT Like Routine: Do you want to win the battle or the war?
Many in the migraine community have heard the common phrase "the migraine brain loves routine." However, a recent study suggests that this advice, while potentially helpful...
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Understanding The Migraine-Cardiovascular Connection
Discover the surprising connection between migraine and cardiovascular health in our latest article. New research reveals how migraine, especially with aura, affects heart health differently than...
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New Research Shows Migraine Patients with Medication Overuse/Adaptation Headache May Have Leaky Gut
A Journal of Headache and Pain study links chronic migraine with medication overuse headache to markers of leaky gut. Key findings and limitations.
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Migraine and Depression: Shared Brain Mechanisms
Learn why migraine and depression are linked through shared brain pathways. 2025 research reveals genetic connections and dual-action treatments for both.
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Ditans
Discover lasmiditan (ditans) - the first new migraine treatment class in 30 years. Learn how this cardiovascular-safe alternative works, clinical trial results, dosing guidelines, and who...
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Anatomical and Functional Consequences of Chronic Migraine
For many people with migraine, their migraine is episodic. Not seeing a neurologist or a headache specialist and following the appropriate treatment plan may result in...
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Choosing Migraine Medications Based on Administration Routes
Complete guide to migraine drug delivery methods: oral tablets, nasal sprays, injections & topical treatments. Compare onset times, effectiveness & side effects for optimal migraine relief....
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New Study Unravels the Complex Relationship Between Migraine and Sleep
A University of Arizona preclinical study found sleep loss raises vulnerability to migraine-like pain, but pain did not disrupt sleep. What it means.
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Semaglutide (Ozempic, GLP-1) and Migraine: What a 189,000-Person Study Found
A nationwide Danish study of 189,392 adults found that starting weight-loss semaglutide was followed by a gradual 7% reduction in triptan use over 12 months. Here...
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Medication Overuse Headache aka Medication Adaptation Headache aka Rebound Headache: A Comprehensive Guide
A clinical guide to medication overuse headache, also called medication adaptation or rebound headache: causes, diagnosis, withdrawal, and prevention.
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Melatonin and Migraine
Melatonin & Migraine
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9 Surprising Migraine Symptoms
Discover the little-known symptoms of migraines and learn how to manage them. We highlight 9 surprising migraine symptoms that you need to be aware of.
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The New Migraine Prevention Guideline: What the AAN and AHS Recommend
The American Academy of Neurology and the American Headache Society have published a joint practice guideline on migraine prevention in adults: 17 recommendations and 52 statements....
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Clinical Predictors for Efficacy of Erenumab (Aimovig) for Migraine
Discover key predictors of Aimovig (erenumab) response in migraine patients. This REFORM study reveals which patients benefit most from CGRP therapy and why timing matters. Evidence-based...
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Eptinezumab (Vyepti) Desensitization Protocol
First-ever eptinezumab (Vyepti) desensitization protocol for migraine patients with hypersensitivity reactions. 10-step hospital-based approach proven safe and effective.
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Migraine Peripheral Nerve Blocks
Complete guide to migraine nerve blocks: how they work, success rates (60-82%), candidacy criteria, safety profile, and what to expect. Evidence-based info for chronic migraine patients...
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Migraine Surgery: Does it make sense?
Migraine surgery involves decompressing various nerves in the face and head that are proposed to trigger migraine attacks. Proponents argue that decompressing these trigger sites can...
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Anatomical and Functional Consequences of Chronic Migraine
Key findings from current research on how chronic migraine affects brain structure and function, recent neuroimaging advances, and associated comorbidities.
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Cluster Headache Treatment: Acute and Preventive
Cluster headache treatment: acute options like oxygen and triptans, bridging therapy, and preventives such as verapamil, explained step by step.
