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Results for “cgrp”
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Fremanezumab for Migraine: What Real-World Use Shows
A 2026 real-world meta-analysis found fremanezumab cut monthly migraine days by nearly 6, with about half of people achieving a 50% or greater drop in attacks....
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Atogepant for Migraine Prevention: What the Data Shows
A new meta-analysis of 6 randomized trials and 3,453 people shows how much atogepant actually reduces monthly migraine days, which dose works best, and what side...
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The American Headache Society Updated its Migraine Prevention Guidelines!
The American Headache Society (AHS), a leading authority on headache treatment, has updated its guidelines to recommend that therapies targeting the calcitonin gene-related peptide (CGRP) can...
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Pharmaceutical Options for Migraine Prevention
A comprehensive guide to medication classes, efficacy, dosing, and considerations for personalized preventive treatment
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Gepants
Discover gepants, the revolutionary CGRP receptor antagonists transforming migraine treatment. Learn about Ubrelvy, Nurtec ODT, Zavzpret, and Qulipta - their mechanisms, efficacy data, safety profiles, and...
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Migraine Pharmaceutical Treatment Pearls
Comprehensive expert guide to migraine treatments: evidence-based recommendations for acute medications (NSAIDs, triptans, gepants), preventive therapies, and special considerations for pregnancy, cardiovascular disease, and other medical...
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Migraine Management During Pregnancy, Breastfeeding, and Pregnancy Planning
This guide provides comprehensive, evidence-based recommendations for migraine management throughout the reproductive journey.
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Migraine Pathophysiology
Comprehensive guide to migraine pathophysiology: brain mechanisms, CGRP pathway, cortical spreading depression, triggers, genetics, and how understanding migraine science guides modern treatments like CGRP inhibitors and...
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Deep Dive into the Pathophysiology of Trigeminal Autonomic Cephalalgias
Explore the complex pathophysiology of trigeminal autonomic cephalalgias (TACs), including the role of the trigeminal autonomic reflex, hypothalamic activation, neuropeptides, and autonomic symptoms. Understand how these...
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Migraine Research - During the week of my absence.
A roundup of migraine studies from one week, including insomnia and migraine disability and cardiovascular risks for pregnant women with migraine.
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Effectiveness and Tolerability of Atogepant (Qulipta) in the Prevention of Migraine
STAR study shows atogepant (Qulipta) effectively reduces migraine days by 56.6% in real-world clinical practice, even for patients with previous treatment failures. Learn about this breakthrough.
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Migraine Preventive Medications: Which Work Best (2026)
A new 199-trial network meta-analysis ranks migraine preventive medications by both effectiveness and tolerability. Here is what it found about beta-blockers, CGRP-targeted therapies, calcium channel blockers,...
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Novel Treatments and Approaches in Migraine Research (as of February 2025)
A roundup of novel migraine treatments in development as of February 2025, from new molecular targets to immune-based approaches.
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Preventive Migraine Medications with a Higher Likelihood of Being Safely Combined
Understanding Drug Compatibility Understanding how different migraine medications work together is important for effective treatment.
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Migraine Medication Underuse: How Insufficient Treatment Can Lead to Chronic Migraine
While effective acute and preventive migraine medications are available, many patients experience migraine progression and chronification due to insufficient, ineffective, or intolerable use of these treatments....
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Medication Overuse/Adaptation Headache
Comprehensive guide to medication overuse headache (MOH/MAH): understand causes, symptoms, and evidence-based treatments. Learn about CGRP therapies, withdrawal protocols, prevention strategies, and breakthrough research showing detox...
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Gepant Adverse Events Chart
A comprehensive analysis of real-world data has uncovered important insights into the safety profiles of gepant medications used for migraine treatment.
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Atogepant and Weight: What a One-Year Study Found
A phase 3 open-label extension followed nearly 600 people taking atogepant [Qulipta] for migraine prevention and tracked their weight for a year. Mean weight went down,...
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Vestibular Migraine
Comprehensive guide to vestibular migraine: symptoms, diagnosis, and evidence-based treatment options for migraine-related vertigo and dizziness. Learn about causes, triggers, medications, and long-term management strategies for...
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Gepants for Migraine: Atogepant & Rimegepant Evidence
A new review of 16 randomized trials breaks down how the gepants atogepant and rimegepant perform for migraine prevention and acute treatment. Here is what the...
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FDA Approves Zavzpret (zavegepant), a New Nasal Spray to Treat Acute Migraine
The latest addition to the arsenal of treatments for acute migraine has been granted approval by the US Food and Drug Administration (FDA).
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Migraine: Men Vs Women
Sex-Based Differences in Migraine
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Dizziness and Migraine: When is it Vestibular Migraine?
Dizziness and migraine: Learn when dizziness is vestibular migraine vs BPPV, Meniere's disease, or vascular causes. Guide covers symptoms, diagnosis, cutaneous allodynia, and treatment options for...
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Choosing the best PRESCRIPTION preventive migraine treatment for you (if you have episodic migraines)!
How to choose a prescription preventive for episodic migraine (fewer than 15 headache days a month), with a quick comparison of the main options.
