(Scroll down for video) Important Concepts: Definition of Cortical Spreading Depression (CSD): A wave of neuronal and glial depolarization that slowly progresses across the cerebral cortex. Role in Migraine: CSD...

Migraine patients may soon have a new treatment option. Recent clinical trials show promising results for Lu AG09222, a monoclonal antibody targeting PACAP, a neuropeptide involved in migraine pathophysiology.

Migraine Symptoms Across All Phases Comprehensive analysis of symptom prevalence throughout the migraine cycle Based on research published in Headache: The Journal of Head and Face Pain | 2024 29...

Discover what white matter lesions mean for migraine patients. This guide explores the latest research on the relationship between migraine and brain changes, offering insights into prevalence, potential causes, and...

Discover the intriguing link between Patent Foramen Ovale (PFO) and migraine. Learn about new research, treatment options, and the potential impact on stroke risk. 

HeadaTerm 2

Unraveling Migraine: A Comprehensive Guide to Understanding and Managing A Complex Neurological Disease

A randomized, double-blind, placebo-controlled study published in Cephalalgia investigated whether sildenafil (Viagra), a phosphodiesterase-5 (PDE-5) inhibitor that increases cGMP levels, could induce migraine attacks in individuals with migraine who were pre-treated with...

It can sometimes be difficult to distinguish between migraine aura and TIA, especially in cases of hemiplegic migraine, migraine with brainstem aura, or retinal migraine. Pay close attention to the...

Many in the migraine community have heard the common phrase "the migraine brain loves routine." However, a recent study suggests that this advice, while potentially helpful in the short-term, may...

The researchers discovered that 3.1% of participants experienced abnormal ECGs or cardiovascular adverse events. Among these, 1.6% encountered more severe complications, such as cerebellar stroke, spontaneous coronary artery dissection, or...

A recent study has found that galanin, a neuropeptide, may be a potential new treatment target for migraine with aura. Galanin significantly reduced the severity and spread of cortical spreading depolarizations...

It's that time again. New misinformation on social media claiming potassium to be a migraine treatment. It is crucial to separate facts from fiction when it comes to the role...

While diagnosis and treatment monitoring of migraine disease largely rely on patient-reported symptoms, the discovery of calcitonin gene-related peptide (CGRP) as a potential biomarker has sparked hope for a more...

A recent study indicates that acid reflux medications, particularly proton pump inhibitors (PPIs), may be associated with a higher risk of migraine and severe headache. Learn about the study's key...

Get HeadaTerm 2 Now If you have migraine disease, you may have heard of Cefaly - the popular FDA-approved device that uses external trigeminal nerve stimulation (eTNS) technology to prevent...

Discover the fascinating findings of a recent MRI study that sheds new light on the brain's inner workings in individuals with migraine, offering hope for better understanding and treatment of...

While effective acute and preventive migraine medications are available, many patients experience migraine progression and chronification due to insufficient, ineffective, or intolerable use of these treatments. This phenomenon, termed "medication...