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Articles
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Fremanezumab for Migraine: What Real-World Use Shows
A 2026 real-world meta-analysis found fremanezumab cut monthly migraine days by nearly 6, with about half of people achieving a 50% or greater drop in attacks....
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What Will They Give Me in the Emergency Department for My Migraine Attack?: Migraine Cocktail Explained
Evidence-Based Pharmacological Treatment of Acute Migraine in the Emergency Department
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Migraine Peripheral Nerve Blocks
Complete guide to migraine nerve blocks: how they work, success rates (60-82%), candidacy criteria, safety profile, and what to expect. Evidence-based info for chronic migraine patients...
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Vitamin B12 Deficiency and Migraine
How vitamin B12 deficiency relates to migraine, what the research shows about B12 levels in people with migraine, and when testing makes sense.
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Migraine, Menopause, and Hormonal Health
Migraine affects women three times more than men, and menopause does not always bring relief. Nearly half of women continue having migraine attacks after menopause. Learn...
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Migraine and Cardiovascular Disease: The Hidden Connection
Migraine increases cardiovascular disease risk. People with migraine with aura face 2x stroke risk. Learn prevention strategies and heart-healthy treatments.
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CGRP and Migraine: The Molecule and the New Drugs
CGRP is the molecule behind the newest migraine drugs. What CGRP is, how it triggers an attack, and how anti-CGRP antibodies and gepants prevent or stop...
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Migraine Surgery: Does it make sense?
Migraine surgery involves decompressing various nerves in the face and head that are proposed to trigger migraine attacks. Proponents argue that decompressing these trigger sites can...
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Acute Migraine Treatment
Complete evidence-based guide to acute migraine treatment for adults. Learn optimal dosing for triptans, NSAIDs, CGRP antagonists & emergency protocols. Includes treatment pearls, medication selection strategies,...
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Evidence-Based Guide to Migraine Nutraceuticals and Herbal Options
Evidence-based guide to natural migraine treatments including riboflavin, magnesium, ginger, and CoQ10. Compare effectiveness, dosing, and safety of 15+ nutraceuticals and herbal remedies for migraine prevention...
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Rimegepant for Migraine Prevention: Real-World Evidence
New real-world data on rimegepant for migraine prevention: a 75 mg every-other-day gepant that also treats attacks. What the GEMA study found on response rates, dosing,...
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Migraine Pathophysiology
Comprehensive guide to migraine pathophysiology: brain mechanisms, CGRP pathway, cortical spreading depression, triggers, genetics, and how understanding migraine science guides modern treatments like CGRP inhibitors and...
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Migraine and Depression: Shared Brain Mechanisms
Learn why migraine and depression are linked through shared brain pathways. 2025 research reveals genetic connections and dual-action treatments for both.
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Primary Stroke Prevention in the Migraine Patient
Learn how migraine increases stroke risk and discover evidence-based prevention strategies from the latest AHA/ASA guidelines. Practical tips on diet, exercise, medication, and hormonal considerations specifically...
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Migraine and Stroke Risk After Menopause: What a 130,000-Woman Study Found
A new Neurology study of 130,000 postmenopausal women followed for two decades finds a history of migraine is linked to a modest increase in ischemic stroke...
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Atogepant for Migraine Prevention: What the Data Shows
A new meta-analysis of 6 randomized trials and 3,453 people shows how much atogepant actually reduces monthly migraine days, which dose works best, and what side...
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Does Ginger Actually Help Migraine? A New Review Finally Grades the Evidence
A new BMJ Evidence-Based Medicine review pooled 8 randomized trials of ginger for migraine and graded every outcome as low or very low certainty. Here is...
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Gepants for Migraine: Atogepant & Rimegepant Evidence
A new review of 16 randomized trials breaks down how the gepants atogepant and rimegepant perform for migraine prevention and acute treatment. Here is what the...
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New Emergency Department Migraine Treatment Guidelines
The American Headache Society (AHS) has released its 2025 guideline update for the acute treatment of migraine in adults presenting to the emergency department. This update,...
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Menstrual Migraine: Why Your Period Triggers Attacks
Migraines that strike around your period are driven by an estrogen drop. Learn the menstrual window, the two types, timed prevention, and the aura safety rule.
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Choosing Migraine Medications Based on Administration Routes
Complete guide to migraine drug delivery methods: oral tablets, nasal sprays, injections & topical treatments. Compare onset times, effectiveness & side effects for optimal migraine relief....
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Cannabis for Migraine: What Randomized Trials Show
A new systematic review graded every randomized trial of cannabinoids for migraine and headache. Vaporized THC plus CBD beat placebo for acute attacks with moderate certainty,...
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Status Migrainosus Guide: A migraine attack lasting 72 hours or more
Status migrainosus is a severe migraine complication lasting over 72 hours requiring emergency treatment. Learn evidence-based management strategies, IV therapy protocols, diagnostic criteria, and prognosis from...
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Migraine Science Archive 2026
Older entries from Today in Migraine Science: plain-language summaries of migraine studies, guidelines and news, each linked to its source.

